EXPAREL, also referred to as "liposomal bupivacaine," can be administered via infiltration, interscalene brachial plexus nerve block, and fascial plane blocks to provide long-lasting non-opioid pain control

More than 9 million patients have received non-opioid EXPAREL since 2012.¹ EXPAREL works locally at the surgical site and uses the DepoFoam® drug delivery technology, which encapsulates bupivacaine in multivesicular liposomes. After injection, DepoFoam® particles gradually release bupivacaine over time, as the lipid membranes are absorbed, prolonging the duration of action of bupivacaine.2,3

The proprietary DepoFoam technology and versatility of administration enables infiltration into the surgical site to produce local analgesia, in the fascial plane to produce regional analgesia as a regional field block or as an interscalene brachial plexus nerve block. EXPAREL may be used across surgical procedures and has demonstrated improved clinical and economic outcomes.


Broad indication across surgical procedures to provide regional analgesia

Interscalene brachial plexus nerve block

Use interscalene brachial plexus nerve block in procedures such as total shoulder arthroplasty and rotator cuff surgeries

Field blocks (ie, TAP & PECS)

Use EXPAREL to provide effective regional field or interfascial plane blocks in a range of procedures

TAP, transversus abdominis plane.