Avoid the burden of pumps and catheters with EXPAREL
Only EXPAREL provides long-lasting pain control in a single dose.
Why risk toxicity with pumps and catheters?5
*Minimum local anesthetic threshold for CNS toxicity is 2000 ng/ml.7
†Data from a single-center cumulative dose toxicity study characterizing serum bupivacaine concentrations over 72 hours in patients undergoing a total knee arthroplasty. Patients in the EXPAREL arm received EXPAREL 266 mg (20 mL) plus 30 mL of bupivacaine 0.5% as a periarticular injection (PAI). Patients in the continuous femoral nerve block arm received a bolus of 20 mL of bupivacaine 0.5% followed by 8 mL/h bupivacaine 0.5% for 48 hours and a PAI of 30 mL of bupivacaine 0.5% during surgery.6
CNS, central nervous system.
In the face of shortages,
EXPAREL requires significantly fewer local anesthetic resources than continuous catheters
One EXPAREL 266 mg (20 ml) single-use vial may require only one vial of bupivacaine‡
Less than one vial of bupivacaine‡ when one EXPAREL 133 mg (10 ml) single-use vial is used in an interscalene brachial plexus nerve
Continuous catheters require up to 10 to 15 vials of bupivacaine‡§