EXPAREL in obstetrics and gynecologic surgery

Administration volume and technique are critical to achieving optimal results

The videos below include a variety of surgical procedures that demonstrate examples of how to administer EXPAREL for optimal pain control and coverage.

C-Section (Infiltration) Performed by Dr Cherot

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This video represents an individual clinician experience with and methodology for using EXPAREL.

Pacira BioSciences, Inc., recognizes that there are other methodologies for administering local anesthetics, as well as individual patient considerations, when selecting the dose for a specific procedure.

Please see Important Safety Information below and refer to the Full Prescribing Information.

More Videos

C-Section (Infiltration)

C-Section (Infiltration) Performed by Dr Cherot

Laparoscopic Hysterectomy

Laparoscopic Hysterectomy Performed by Dr Miller

TAP In Open Hysterectomy

TAP In Open Hysterectomy Performed by Dr Hutchins

Open Myomectomy

Open Myomectomy Performed by Dr McCarus

Multimodal approaches with or without ERAS protocols have demonstrated benefits in obstetric and gynecologic procedures

  • Reduced opioid use and risk of ORAEs1-5
  • Fewer postsurgical complications3
  • Higher patient satisfaction2,3
  • Earlier mobility1,6
  • Shorter hospital LOS3,4
  • Reduced healthcare costs4

Clinical data support the use of EXPAREL

Transversus abdominis plane block with liposomal bupivacaine for pain control after cesarean delivery

Transversus abdominis plane block with liposomal bupivacaine for pain after cesarean delivery in a multicenter, randomized, double-blind, controlled trial

Leading medical societies recommend opioid-minimizing pain management strategies to enhance recovery after obstetric and gynecologic procedures


  • A stepwise, multimodal pain management strategy, including local anesthetics delivered by wound infiltration or TAP block, is recommended to control pain and minimize opioid administration
  • Postoperative minimization of opioid use reduces nausea and vomiting, impairment of bowel function, delayed mobilization, and pulmonary morbidity


  • Multimodal analgesia, including wound infiltration or regional blocks (eg, TAP block), should be used to reduce pain, improve mobilization, reduce opioid use in the hospital after discharge, and decrease opioid side effects


  • Advocate for the goal of reducing opioid misuse, and optimizing availability and use of non-opioid methods of pain control


  • Avoiding opioid use within a multimodal postoperative analgesia pathway, with greater emphasis on non-opioid medications such as liposomal bupivacaine, can improve patient experience and functional recovery after surgery

ACOG, American College of Obstetrics and Gynecologists; ERAS, enhaced recovery after surgery; LOS, length of stay; SGO, Society of Gynecologic Oncology; SOAP, Society for Obstetric Anesthesia and Perinatology; ORAE, opioid-related adverse events; TAP, transversus abdominis plane.