Administration volume and technique are critical to achieving optimal results
The videos below include a variety of surgical procedures that demonstrate examples of how to administer EXPAREL for optimal pain control and coverage.
Rotator Cuff RepairPerformed by Dr Sethi
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This video represents an individual clinician experience with and methodology for using EXPAREL.
Pacira BioSciences, Inc., recognizes that there are other methodologies for administering local anesthetics, as well as individual patient considerations, when selecting the dose for a specific procedure.
Rotator Cuff Repair
Rotator Cuff Repair Performed by Dr Sethi
Rotator Cuff Repair 2 (Interscalene Brachial Plexus Nerve Block)
Rotator Cuff Repair 2 (Interscalene Brachial Plexus Nerve Block) Performed by Dr Hutchins
Total Shoulder Arthroplasty
Total Shoulder Arthroplasty Performed by Dr Routman
Cost and value
Multimodal protocol and results: shoulder arthroplasty
Retrospective study comparing the efficacy of EXPAREL and dexamethasone intraoperatively as part of multimodal pain management (n=31) versus standard multimodal pain management (n=24) in patients undergoing elective shoulder arthroplasty.
- Single-injection interscalene block
- Acetaminophen 1000 mg intravenously
- Gabapentin 600 mg orally
- Oxycodone 10 mg orally
- Celecoxib 200 mg orally
- Standard multimodal group: none
- EXPAREL group:
- EXPAREL 266 mg/20 mL + saline 20 mL + 0.25% bupivacaine HCl with epinephrine 10 mL*
- Dexamethasone 8 to 10 mg intravenously
- Ketorolac intravenously
- Acetaminophen intravenously
- Gabapentin orally
- Oxycodone 5 mg and 10 mg orally for mild to moderate pain
- Hydromorphone 0.5 mg, 1 mg, and 2 mg intravenously for moderate to severe pain
Patients who received multimodal analgesia with EXPAREL
- 3.5 vs 7.5 VAS pain score on POD 1 (P<0.001)
- 20 mg vs 40.5 mg in cumulative utilization (P<0.001)
- 1 day vs 2 days (P<0.001)
*The use of EXPAREL in combination with epinephrine is not part of the approved label.
†Opioid intake measured in MED (mg).
LOS, length of stay; MED, morphine equivalent dosing; POD, postoperative day; VAS, visual analog scale; ISBP, interscalene brachial plexus.