Nurse and patient smiling as patient is discharged from hospital post-nerve block surgery

Clinical and economic value outcomes with EXPAREL

Cost & Value

EXPAREL is available in 133 mg (10 mL) for $180.35 and 266 mg (20 mL) doses for $334.18. The 133 mg (10 mL) and 266 mg (20 mL) doses of EXPAREL are available in cartons of 4 and 10 vials. For more information please visit How to order EXPAREL.

Information below helps review the value of EXPAREL in a multimodal pain management protocol that can lead to fewer opioids, better pain control, and shorter length of stay (LOS). These, in turn, can lead to fewer patient complications and reduced hospital costs per patient.

Select Procedure Type
Orthopedic & Spine

Total Joint Arthroplasty1: ASC in New Jersey

Study Methods

  • 51 consecutive TJA procedures performed with the use of EXPAREL by 3 fellowship-trained adult reconstruction surgeons
    • Procedures included THA, TKA, and UKA
  • Retrospective review of outpatient medical records and preoperative and postsurgical clinical charts

Safety Outcomes

  • All adverse events were minor and treated within the ASC without the need for overnight observation or hospitalization

Clinical and Economic Outcomes

In patients who received EXPAREL for analgesia
  • 84%

    of patients surveyed (n=19) reported pain level as expected and well controlled

  • 0%

    of patients required
    an ED visit for uncontrolled pain
    and postsurgical transfusion

  • 0%

    of patients experienced
    a reported adverse
    event that required
    prolonged care or
    hospitalization

  • 98%

    of patients
    were discharged
    to home

    • 1 THA patient elected to go to a rehabilitation facility prior to surgery
  • 80%

    of patients
    surveyed (n=19)
    would recommend
    the ASC to friends
    and family

 

TJA (N=51)

  • Preoperative regimen
    • 1 dose each of celecoxib, oxycodone hydrochloride extended release, and gabapentin
  • Perioperative regimen
    • 1 dose of intravenous acetaminophen and 2 doses of intravenous dexamethasone
  • Intraoperative regimen*
    • Periarticular injection of EXPAREL, epinephrine, morphine, methylprednisolone, and cefazolin in 20 mL of normal saline
  • Postsurgical regimen
    • Celecoxib, oxycodone hydrochloride extended release for 7 days, and oxycodone for breakthrough pain

THA (n=22)

  • Average surgical time was 132 minutes and total LOS was 6.3 hours
  • Received a lumbar epidural catheter in preoperative holding and propofol sedation intraoperatively

TKA (n=15)

  • Average surgical time was 130 minutes and total LOS was 7.1 hours
  • Received a single-dose femoral nerve block, a single-dose tibial nerve block, and an adductor canal catheter block in preoperative holding

UKA (n=14)

  • Average surgical time was 130 minutes and total LOS was 6.2 hours
  • Received a single-dose femoral nerve block, a single-dose tibial nerve block, and an adductor canal catheter block in preoperative holding

TJA, total joint arthroplasty; TKA, total knee arthroplasty; UKA, unicondylar knee arthroplasty.

*The use of EXPAREL in combination with epinephrine is not part of the approved label.