Administration volume and technique are critical to achieving optimal results
The videos below include a variety of surgical procedures that demonstrate examples of how to administer EXPAREL for optimal pain control and coverage.
Arthroscopic Rotator Cuff RepairPerformed by: Dr Sethi
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This video represents an individual clinician experience with and methodology for using EXPAREL.
Pacira BioSciences, Inc., recognizes that there are other methodologies for administering local anesthetics, as well as individual patient considerations, when selecting the dose for a specific procedure.
Please see Important Safety Information below and refer to the Full Prescribing Information.
More Videos
Arthroscopic Rotator Cuff Repair Performed by: Dr Sethi
Interscalene Brachial Plexus Nerve Block in Rotator Cuff Repair Performed by: Dr Hutchins
Reverse Total Shoulder Arthroplasty Performed by: Dr Routman
Case reports
Cost and value
Multimodal protocol and results: shoulder arthroplasty
Study design1
Retrospective study comparing the efficacy of EXPAREL and dexamethasone intraoperatively as part of multimodal pain management (n=31) versus standard multimodal pain management (n=24) in patients undergoing elective shoulder arthroplasty.
Multimodal protocol
PREOPERATIVE
- Single-injection interscalene block
- Acetaminophen 1000 mg intravenously
- Gabapentin 600 mg orally
- Oxycodone 10 mg orally
- Celecoxib 200 mg orally
INTRAOPERATIVE
- Standard multimodal group: none
- EXPAREL group:
- EXPAREL 266 mg/20 mL + saline 20 mL + 0.25% bupivacaine HCl with epinephrine 10 mL*
- Dexamethasone 8 to 10 mg intravenously
POSTSURGICAL
- Ketorolac intravenously
- Acetaminophen intravenously
- Gabapentin orally
- Oxycodone 5 mg and 10 mg orally for mild to moderate pain
- Hydromorphone 0.5 mg, 1 mg, and 2 mg intravenously for moderate to severe pain
Patients who received multimodal analgesia with EXPAREL
- 3.5 vs 7.5 VAS pain score on POD 1 (P<0.001)
- 20 mg vs 40.5 mg in cumulative utilization (P<0.001)
- 1 day vs 2 days (P<0.001)
*The use of EXPAREL in combination with epinephrine is not part of the approved label.
†Opioid intake measured in MED (mg).
LOS, length of stay; MED, morphine equivalent dosing; POD, postoperative day; VAS, visual analog scale; ISBP, interscalene brachial plexus.