Change the face of postsurgical recovery

EXPAREL for single-dose infiltration or as an interscalene brachial plexus nerve block provides significant long-lasting pain control while reducing opioid use.


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contact reimbursement@pacira.com or call the EXPAREL reimbursement hotline: 855-793-9727

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How to Use EXPAREL: Videos and Case Reports by Procedure
Select a surgical site and procedure to see EXPAREL in practice

EXPAREL in interscalene brachial plexus nerve block

46% reduction in pain vs placebo (P<0.0001)2*

78% reduction in opioid use vs placebo (P<0.0001)3*

No cumbersome pumps or catheters necessary

*Results from a phase 3, double-blind, randomized, controlled trial that compared the postsurgical analgesia efficacy, safety, and pharmacokinetics of EXPAREL 133 mg (10 mL) and placebo in a total shoulder arthroplasty or rotator cuff repair. Primary and secondary end points: pain intensity through 48 hours postsurgery, as measured by area under the curve of visual analog scale pain intensity scores, and total postsurgical opioid consumption.2 Rescue opioids for pain were available upon patient request.

The clinical benefit of the decrease in opioid consumption was not demonstrated in pivotal trials.

EXPAREL vs bupivacaine HCI in total knee arthroplasty4

Results from an EXPAREL phase 4, double-blind, randomized, controlled trial that compared the efficacy and safety of EXPAREL 266 mg (20 mL) (n=70) and bupivacaine HCl (n=69) in a total knee arthroplasty study. Primary end points: area under the curve of visual analog scale pain intensity scores 12 to 48 hours postsurgery; total opioid consumption 0 to 48 hours postsurgery. Rescue opioids for pain were available upon patient request.

*The clinical benefit of the decrease in opioid consumption was not demonstrated in pivotal trials.

Learn more about opioid-free EXPAREL

A light bulb icon to reveal site tip for easy navigationHow to Use EXPAREL: Videos and Case Reports by Procedure
procedures

Bariatric

Laparoscopic Sleeve Gastrectomy

Breast

Bilateral Mastectomy
Breast Reconstruction

Colorectal/General

Abdominal Wall Reconstruction
Colectomy
Hemorrhoidectomy
Small Bowel Resection

Obstetrics/Gynecology

C-Section (Infiltration)
C-Section (TAP)
Laparoscopic Hysterectomy
Open Hysterectomy
Open Myomectomy

Oral/Maxillofacial

Bilateral TMJ Arthroplasty
Full Maxillary Reconstruction Infiltration
Oral Surgery Infiltration Technique
Third-Molar Extraction

Orthopedic

Ankle Fracture
Bone-Patellar Tendon-Bone ACL Reconstruction
Bunionectomy
Hip Arthroplasty
Hip Fracture (Fascia Iliaca Block)
Left Unstable Intertrochanteric Hip Fracture Fixation
Quad Tendon ACL Arthroscopic Reconstruction
Total Hip Arthroplasty
Total Hip Arthroplasty - Anterior Approach
Total Knee Arthroplasty

Shoulder

Rotator Cuff Repair
Rotator Cuff Repair 1 (Interscalene Brachial Plexus Nerve Block)
Rotator Cuff Repair 2 (Interscalene Brachial Plexus Nerve Block)
Total Shoulder Arthroplasty

Spine

Percutaneous Lumbar Fusion
C-Section (Infiltration)
Hip Fracture (Fascia Iliaca Block)
Quad Tendon ACL Arthroscopic Reconstruction
Rotator Cuff Repair 1 (Interscalene Brachial Plexus Nerve Block)

Anesthesiologist

Bariatric Surgeon

General Surgeon

Injection technique is critical for optimal analgesia with EXPAREL

Watch experts administer EXPAREL
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