Oral AND MAXILLOFACIAL Surgery

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Oral and Maxillofacial

ASK YOUR DOCTOR ABOUT NON-OPIOID PAIN MANAGEMENT AFTER ORAL AND MAXILLOFACIAL SURGERY.

Some of the most common concerns about surgery are the amount of pain involved and what to expect when recovering. Well-controlled pain can influence your recovery. Numbing medication is often used in the areas involved with oral surgery procedures. The medication will wear off and patients experience pain differently. Your doctor will have a pain management plan that includes different combinations of medications, including opioid and non-opioid options. In addition to managing pain after surgery, the plan is aimed at helping you reach important recovery goals such as drinking and eating. Talk to your doctor about a pain management plan that is right for you and your type of surgery. Create your discussion guide now.

Oral (mouth) or maxillofacial (face and jaw) surgery covers many types of procedures, including

Facial plastic surgery
Temporomandibular joint (TMJ) surgery
Wisdom tooth removal
Reconstructive or corrective
surgery

Facial plastic surgery
Temporomandibular joint (TMJ) surgery
Reconstructive or corrective
surgery
Wisdom tooth removal

70% of patients

are prescribed opioids for postsurgical pain after a third-molar extraction

33% of young adults

who take prescription opioids are at higher risk of future opioid misuse

SIDE EFFECTS from opioids can slow down your recovery and may cause nausea, vomiting, and constipation. Opioids may make you feel drowsy or confused.

100 million opioids go unused by patients every year—these pills can be misused and abused by others.

Young adults who take opioids after oral surgery are 3 times more likely to become long-term users.

While many patients may receive opioids after surgery, there are other options for managing pain after surgery that may help you during recovery. That's why it's important to discuss these options with your doctor.

NON-OPIOID EXPAREL PROVIDES LONG-LASTING PAIN RELIEF AFTER SURGERY

EXPAREL is given during surgery as part of an opioid-minimizing approach and controls pain for the first few days after surgery, when you need it most
EXPAREL works by numbing the area of your body where your surgery was performed, unlike opioids, which affect your whole body

In wisdom tooth removal surgeries, patients given EXPAREL^*^†

Reported less pain

Required fewer opioids^‡

^*For patients undergoing the study defined protocols.

^†Based on clinical studies of surgeries using EXPAREL as an alternative to standard of care.

^‡The clinical benefit of the decrease in opioid consumption was not demonstrated in the pivotal trials.

FIND A DOCTOR WHO USES EXPAREL

If you are planning for surgery and think EXPAREL is right for you, find doctors and facilities that offer EXPAREL.

Indication

EXPAREL^® (bupivacaine liposome injectable suspension) is indicated to produce postsurgical local analgesia via infiltration in patients aged 6 years and older and regional analgesia in adults via an interscalene brachial plexus nerve block, sciatic nerve block in the popliteal fossa, and an adductor canal block. Safety and efficacy have not been established in other nerve blocks.

Important Safety Information

EXPAREL should not be used in obstetrical paracervical block anesthesia.

In studies in adults where EXPAREL was injected into a wound, the most common side effects were nausea, constipation, and vomiting.

In studies in adults where EXPAREL was injected near a nerve, the most common side effects were nausea, fever, headache, and constipation.

In the study where EXPAREL was given to children, the most common side effects were nausea, vomiting, constipation, low blood pressure, low number of red blood cells, muscle twitching, blurred vision, itching, and rapid heartbeat.

EXPAREL can cause a temporary loss of feeling and/or loss of muscle movement. How much and how long the loss of feeling and/or muscle movement depends on where and how much of EXPAREL was injected and may last for up to 5 days.

EXPAREL is not recommended to be used in patients younger than 6 years old for injection into the wound, for patients younger than 18 years old for injection near a nerve, and/or in pregnant women.

Tell your health care provider if you or your child has liver disease, since this may affect how the active ingredient (bupivacaine) in EXPAREL is eliminated from the body.

EXPAREL should not be injected into the spine, joints, or veins.

The active ingredient in EXPAREL can affect the nervous system and the cardiovascular system; may cause an allergic reaction; may cause damage if injected into the joints; and can cause a rare blood disorder.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.